We put Hartz flea and tick topical on him after getting him trained on his leash. Within in an hour he was completely out of it. We washed it off of him with dawn dish soap and water. He began seizing and by the time we got him to the animal hospital it was too late. Please, please do not use this brand. I would give anything to have my baby back. He was so happy and healthy. Always got his yearly checkups, never missed a vaccanations, and we only fed him the best of the best. I wish I would have gone back and done my research. Hartz needs to be shut down immediately.