I had put these drops on my 5 pound Yorkie poo. A couple days later she went outside and literally fell over and couldn’t get up for a few minutes. A few days later, my 60 pound pit mix did the same thing. She too fell down and fought to get back up with no luck until a few minutes later. Do not use these drops if you love your animals as much as I do. I immediately put all my dogs in the tub and just scrubbed and scrubbed them.